Published January 22, 2003
by Informa Healthcare .
Written in English
|Contributions||Robert Strieter (Editor), Steven L. Kunkel (Editor), Theodore Standiford (Editor)|
|The Physical Object|
|Number of Pages||448|
This reference discusses the role of chemokines in mediating leukocyte trafficking, angiogenesis, tumor cell metastasis, host defense, trauma-induced lung injury, and the progression of AIDS in the lung, and studies cytokines as natural agents for modulating diseases that affect the by: 6. Chemokines in non-small cell lung cancer. In the last decade, several clinicopathological studies have focused on establishing whether there are associations between the expression level of chemokines and/or their receptors in tumor tissue, patient survival or development of by: Acute lung injury (ALI) or the acute respiratory distress syndrome (ARDS) is a devastating syndrome, with an incidence of approximately , in the United States and a mortality approaching 40% ().ALI is defined by the presence of bilateral pulmonary infiltrates, severe hypoxemia, and the absence of left atrial hypertension ().Causes of ALI may be direct Cited by: Book Review: Chemokines in the Lung. Robert M Strieter MD, Steven L Kunkel PhD, and Theodore J Standiford MD, editors. (Lung Biology in Health and Disease series, Volume , Claude Lenfant, executive editor).Author: Joan G Clark.
Book Condition: A copy that has been read, but remains in clean condition. All pages are intact, and the cover is intact. The spine may show signs of wear. Pages can include limited notes and highlighting, and the copy can include previous owner : Hardcover. James E. Pease, Timothy J. Williams, in Asthma and COPD (Second Edition), Publisher Summary. Chemokines have multiple roles in the organization of the immune system under basal conditions and during infection, and are also involved in angiogenesis. A crucial role of chemokines is the recruitment of different types of leukocytes from the blood to the sites of . CC chemokines. The CC chemokine (or β-chemokine) proteins have two adjacent cysteines (amino acids), near their amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called CC chemokine ligands -1 to ; CCL10 is the same as CCL9. Chemokines of this subfamily usually contain four cysteines (C4-CC InterPro: IPR Numerous antibodies, receptor-blocking mutant chemokines, and small molecules are being evaluated for the treatment of asthma and other inflammatory lung diseases (Table 3). Orally active small molecules represent the best approach for generating chemokine receptor antagonists with the greatest therapeutic by:
Get this from a library! Chemokines in the lung. [Robert M Strieter; S L Kunkel; Theodore J Standiford;] -- Discusses the role of chemokines in mediating leukocyte trafficking, angiogenesis, tumour cell metastasis, host defence, trauma-induced lung injury, and the progression of AIDS in the lung. The text. The fact that chemokine receptors are differentially expressed on T‐cell subsets and that this differential expression results in selective migration of Th1 and Th2 cells to particular chemokines has led to the hypothesis that chemokines are responsible for the selective recruitment of antigen‐specific Th2 cells to the lung following Cited by: Chemokines in Lung Cancer. Chemokines are chemotactic cytokines that, in the context of cancer, appear to be important in either promoting tumor . Cytokines are critical to the immune response. Find out what it means for lung health. When living with a chronic lung disease such as chronic obstructive pulmonary disease (COPD), pulmonary fibrosis, or emphysema, chronic inflammation is a common condition of the disease’s inflammation within the lungs tends to expand airways and .